A jovem enfermeira Kathy (Sharni Vinson) começa a trabalhar num isolado hospital psiquiátrico, dirigido pelo doutor Roget (Charles Dance). Todos os pacientes do local encontram-se em estado de coma, e servem como cobaias para os experiementos do médico. Patrick (Jackson Gallagher) é o principal alvo dos testes e objeto de fascínio de Kathy. Mas logo o interesse transforma-se em preocupação e medo quando ela percebe que Patrick possui poderes telecinéticos e esta obcecado por ela.
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